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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPT1B All Species: 23.94
Human Site: Y222 Identified Species: 47.88
UniProt: Q92523 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92523 NP_001138607.1 772 87801 Y222 T A P R L Q K Y L V L K S W W
Chimpanzee Pan troglodytes XP_525636 843 95334 Y293 T A P R L Q K Y L V L K S W W
Rhesus Macaque Macaca mulatta XP_001116383 769 87263 Y260 T A P R L Q K Y L V L K S W W
Dog Lupus familis XP_538305 772 87798 Y222 T A P R L Q K Y L V L K S W W
Cat Felis silvestris
Mouse Mus musculus Q924X2 772 88199 Y222 T A P R L Q K Y L V L K S W W
Rat Rattus norvegicus Q63704 772 88198 Y222 I A P R L Q K Y L V L K S W W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90YJ9 640 72605 S171 Q Y Y G L F S S Y R L P G H T
Frog Xenopus laevis Q7ZXE1 659 74538 F190 A K S D T L T F R K L I R F V
Zebra Danio Brachydanio rerio B2ZGJ1 637 71821 Y167 Y N K V F T S Y R L P G T K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07668 721 81310 N222 R A A S R E K N Q P L C M A Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P32756 627 71299 E158 Q K L Q M C M E Q Y D R V L S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32796 670 77223 V201 I K D E S L P V E I I K G M P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 90.1 90.6 N.A. 87 86 N.A. N.A. 23.7 24.3 23.8 N.A. 22.1 N.A. 21.7 N.A.
Protein Similarity: 100 91.3 91.9 96.5 N.A. 94 92.7 N.A. N.A. 41.1 41.8 40.7 N.A. 39.3 N.A. 38.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 13.3 6.6 6.6 N.A. 20 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 13.3 20 20 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 59 9 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 9 9 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 0 0 9 0 9 0 9 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 9 9 0 9 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 0 9 17 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 17 0 0 0 0 0 0 0 0 9 9 9 0 0 0 % I
% Lys: 0 25 9 0 0 0 59 0 0 9 0 59 0 9 0 % K
% Leu: 0 0 9 0 59 17 0 0 50 9 75 0 0 9 0 % L
% Met: 0 0 0 0 9 0 9 0 0 0 0 0 9 9 0 % M
% Asn: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 50 0 0 0 9 0 0 9 9 9 0 0 9 % P
% Gln: 17 0 0 9 0 50 0 0 17 0 0 0 0 0 9 % Q
% Arg: 9 0 0 50 9 0 0 0 17 9 0 9 9 0 0 % R
% Ser: 0 0 9 9 9 0 17 9 0 0 0 0 50 0 9 % S
% Thr: 42 0 0 0 9 9 9 0 0 0 0 0 9 0 17 % T
% Val: 0 0 0 9 0 0 0 9 0 50 0 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 50 % W
% Tyr: 9 9 9 0 0 0 0 59 9 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _